Just a quick Intervention:
I have my Ryzen 5800x with TPM 2.0 enabled on the motherboard. Windows 11 is working flawless, for now Linux partition (Debian) is having 0 issues, also with the TPM turned on.
So if the module increase system security and privacy, I won’t see any motivation about turning off.
So my advice is keeping it enabled, in the end on modern PCs I think advantages are more then disvantages.